In Vitro Dedifferentiation of Melanocytes from Adult Epidermis
نویسندگان
چکیده
منابع مشابه
In Vitro Dedifferentiation of Melanocytes from Adult Epidermis
In previous work we described a novel culture technique using a cholera toxin and PMA-free medium (Mel-mix) for obtaining pure melanocyte cultures from human adult epidermis. In Mel-mix medium the cultured melanocytes are bipolar, unpigmented and highly proliferative. Further characterization of the cultured melanocytes revealed the disappearance of c-Kit and TRP-1 and induction of nestin expre...
متن کاملDedifferentiation of Adult Human Myoblasts Induced by CNTF in Vitro
1 Department of neurophysiology, Institute of Basic Medical Sciences, 27 Taiping Road, Beijing 100850, China 2 Institute of Space Medical Engineering, 1 YuanmingYuan West Road, Beijing 100094, China 3 Department of Biochemistry and Molecular Biology, Peking University Health Science Center, 38 Xueyuan Road, Beijing 100083, China 4 Children’s Hospital of Pittsburgh, 5646 Darlington Road, Pittsbu...
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̈ See article by Rucker-Martin et al. [3] (pages 38 –52) 2 . Structural remodeling of atrial myocytes in this issue. Apart from clear degenerative changes in fibrillating atria of patients which have been reported earlier by the same group and others [4,5], the present study shows that 1 . Introduction in such patients remodeling of the myocyte structure (dedifferentiation) and the surrounding c...
متن کاملIn Vivo Dedifferentiation of Adult Adipose Cells
INTRODUCTION Adipocytes can dedifferentiate into fibroblast-like cells in vitro and thereby acquire proliferation and multipotent capacities to participate in the repair of various organs and tissues. Whether dedifferentiation occurs under physiological or pathological conditions in vivo is unknown. METHODS A tissue expander was placed under the inguinal fat pads of rats and gradually expande...
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Ciliary neurotrophic factor (CNTF) is primarily known for its important cellular effects within the nervous system. However, recent studies indicate that its receptor can be highly expressed in denervated skeletal muscle. Here, we investigated the direct effect of CNTF on skeletal myoblasts of adult human. Surprisingly, we found that CNTF induced the myogenic lineage-committed myoblasts at a cl...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2011
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0017197